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Recently completed projectsElectronic marketplace for parallel medicinal chemistry allows world-wide transactions in an environment that provides IP security and tools for management of chemical structures. This was a project that our principal, Dr. Vladimir Makarov, has recently completed for a Fortune 50 pharmaceutical client. We regret that because of client confidentiality we are unable to provide the URL to that system. DiversiLab Web-based molecular fingerprint analysis system for microbial identification and classification. Developed by Dr. Keith Steward, and marketed by bioMérieux SA, France. SpectralWare array CGH analysis system for detecting Human Cytogenetic Lesions. Used by Cytogene. Developed by Dr. Keith Steward for Spectral Genomics, and later acquired by Perkin Elmer. FDA-approved on-line glaucoma diagnostic tool. This is the only software of its kind that was clinically tested and is registered by the FDA. Dr. Vladimir Makarov of the IFX team was the primary project manager and the co-sponsor of this development. Peristat web site is supported by Lighthouse International and was developed with assistance of physicians from the Doheny Eye Institute. |
Would you like to add your project to this list? Please contact us.
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Recent opinionsWhat our clients, collaborators and colleagues say about us... For Keith: "As a lead for PerkinElmer's next generation CGH Array (DNA chip) product, I benefited tremendously from Keith's Informatics expertise and hard work. This was a huge development project, involving massive amounts of data that needed to be managed, processed, and analyzed in a short period of time, and with a strict requirement for high quality. Keith quickly delivered an advanced informatics platform that provided everything that was needed: a fast LIMS-like database, automated sequence data analysis, a fully automated quality-driven CGH Array Design tool, and a slick Chip Readiness Dashboard, among many other capabilities. The next gen chip product would not have been possible without Keith's extraordinary efforts. I highly recommend him."
For Vladimir: "Vladimir worked closely with one of my teams. We were impressed by his professionalism, his creativity and his ability to deliver quality while staying in time and on budget. Besides that, he has a great sense of humor making the work experience more enjoyable. Organizations benefit when Vladimir works for them."
For Jeff: "Systems Biology is a relatively new field in Plant Science and Jeff has enabled us to pursue genomics, transcriptomics and proteomics in a way that few other plant research groups can match. Jeff has provided us with the tools, including databases such as TOBFAC, that we have used extensively. We have been able to publish three articles and obtain two competitive grants within the last 12 months and this is just the start. This would not have been possible without Jeff's expertise. He is an indispensible member of our team and I highly recommend him."
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Our other achievementsWe conduct original research, publish and teach in the field of computer applications to biotechnology and medicine. Before becoming consultants IFXworks founding members contributed to some high-profile research projects, authored numerous papers and became co-inventors for over 30 United States and international patents. SoftwareProtein Resource Center (PRC) for biodefense proteomics research at the The National Institute of Allergy and Infectious Diseases was developed with contribution by Dr. Chen. It is anticipated that this proteomics data management system will discover potential targets for the next generation of vaccines, therapeutics and diagnostics to help devise protection against biologic weapons. Cowpea genomics knowldgebase. Find metabolic pathways, search for simple sequence repeats (SSRs), or use the annotated genomics database. Co-authored by Dr. Chen. Tobacco regulatory transcription factor database The most wide-ranging database of transcription factors in tobacco and probably in any plant species. Co-authored by Dr. Chen. PublicationsChen X., Laudeman T. W., Rushton P. J., Spraggins T. A., Timko M. P., "CGKB: an annotation knowledge base for cowpea (Vigna unguiculata L.) methylation filtered genomic genespace sequences", BMC Bioinformatics, 2007, v. 8 p. 129. Link Rushton P. J., Bokowiec M. T., Laudeman T. W., Brannock J. F., Chen X., Timko M. P., "TOBFAC: the database of tobacco transcription factors", BMC Bioinformatics, 2008, v. 9, p. 53 Link Lu G., Jiang L., Helikar R., Rowley T. W., Zhang L., Chen X., Moriyama E. N., "GenomeBlast: a web tool for small genome comparison", BMC Bioinformatics, 2006, v. 7(Suppl 4), p. S18 Link Timko M. P., Rushton P. J., Laudeman T. W., Bokowiec M. T., Chipumuro E., Cheung F., Town C. D., Chen X., "Sequencing and analysis of the gene-rich space of cowpea", BMC Genomics, 2008, v. 9, p. 103 Link Rushton P. J., Bokowiec M. T., Han S., Zhang H., Brannock J. F., Chen X., Laudeman T. W., Timko M. P., "Tobacco transcription factors: novel insights into transcriptional regulation in the Solanaceae", Plant Physiol., 2008, v. 147, p. 280 Link Makarov V. A., "Computer programs for eukaryotic gene prediction", Briefings in Bioinformatics, 2002, v. 3, p. 195 Link Makarov V. A., Pettitt B. M., Feig M., "Solvation and Hydration of Proteins and Nucleic acids: a Theoretical View of Simulation and Experiment", Accounts of Chemical Research, 2002, v. 35, p. 376 Link PatentsInternational patent WO/2003/067504 |
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Our pledge to youHave you ever heard this old adage about consultants, "When you are not part of the solution, there is good money to be made in being part of the problem"? We work very hard to never hear this from our customers.
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